Styled by Pininfarina under the direction of Ferrari's Frank Stephenson, the 599 GTB debuted at the Geneva Motor Show in February 2006. Its name came from its engine displacement, Gran Turismo Berlinetta nature, and Ferrari's Fiorano test track.
Unlike its predecessor, the 599 was built from scratch and had various new features including a modified variant of Enzo's 6.0L V12 engine, a Formula 1 derived traction control system, advanced suspensions, and an option for a sequential gearbox and carbon ceramic brakes.
The 599 GTB received a sportier HGTE package in 2008. Introduction of the track-only 599XX followed in 2009 and its road-legal variant, the 599 GTO, was released in 2010. The 599 lineup was succeeded by the F12berlinetta.